Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | TK2 | O00142 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7116002 | 0.80 | LMNA (0.43) | TK1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL7115997 | 0.80 | LMNA (0.43) | TK1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL1129572 | 0.79 | LMNA (0.55) | TK1LMNATSHRBLMPMP22 | |
| SCHEMBL6760136 | 0.79 | LMNA (0.55) | TK1LMNATSHRBLMPMP22 | |
| SCHEMBL1130181 | 0.79 | LMNA (0.55) | TK1LMNATSHRBLMPMP22 | |
| SCHEMBL7701755 | 0.79 | LMNA (0.55) | TK1LMNATSHRBLMPMP22 | |
| SCHEMBL6753208 | 0.79 | SMN1; SMN2 (0.54) | TK1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL6752642 | 0.79 | LMNA (0.60) | TK1LMNASMN1; SMN2TSHRPMP22 | |
| SCHEMBL1129570 | 0.79 | LMNA (0.55) | TK1LMNATSHRBLMPMP22 | |
| SCHEMBL6314490 | 0.79 | LMNA (0.55) | TK1LMNATSHRBLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1361227-A2 | [5-carboxamide or 5-fluoro]-[2', 3'-unsaturated or 3'-modifield]-pyrimidine nucleosides | Emory University (US) | 2003-11-12 | — | — | EP | claimed |