Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7121878 | 0.91 | L3MBTL1 (0.46) | KDM4EL3MBTL1ATMMAPK8KMT2A | |
| SCHEMBL19992961 | 0.83 | KDM4E (0.47) | KDM4EL3MBTL1ATMMAPK8KMT2A | |
| SCHEMBL7124307 | 0.80 | GPR3 (0.41) | KDM4EALDH1A1MAPTHTR2AGLA | |
| Hydrochloric Acid SCHEMBL7117815 | 0.78 | L3MBTL1 (0.44) | KDM4EL3MBTL1ATMMAPK8KMT2A | |
| Hydrochloric Acid SCHEMBL7125860 | 0.78 | L3MBTL1 (0.44) | KDM4EL3MBTL1ATMMAPK8KMT2A | |
| SCHEMBL7128815 | 0.78 | KDM4E (0.44) | KDM4EL3MBTL1ATMMAPK8KMT2A | |
| Hydrochloric Acid SCHEMBL7119552 | 0.78 | L3MBTL1 (0.44) | KDM4EL3MBTL1ATMMAPK8KMT2A | |
| SCHEMBL7128806 | 0.77 | KDM4E (0.43) | KDM4EL3MBTL1ATMMAPK8KMT2A | |
| SCHEMBL7117683 | 0.77 | KDM4E (0.43) | KDM4EL3MBTL1ATMMAPK8KMT2A | |
| Hydrochloric Acid SCHEMBL7117732 | 0.75 | L3MBTL1 (0.42) | KDM4EL3MBTL1ATMMAPK8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030148877-A1 | Metallocenes and catalysts for olefin-polymerisation | BASELL TECHNOLOGY COMPANY BV (NL) | 2003-08-07 | — | — | US | disclosed |
| EP-0952978-B1 | METALLOCENES AND CATALYSTS FOR OLEFIN-POLYMERISATION | BASELL POLYOLEFINE GMBH (DE) | 2003-01-22 | — | — | EP | disclosed |
| US-6451724-B1 | BIS(N-METHYL-5,10-DIHYDROINDENO(1,2-B)INDOL-10 -YL)TITANIUM DICHLORIDE | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030148877-A1 | Metallocenes and catalysts for olefin-polymerisation | MT-CO1, CPNE4, MT-CO3 | KDM4E 3169/4885L3MBTL1 94/4885ATM 4428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.