SCHEMBL712647

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26688770	0.83	TSHR (0.48)	ALDH1A1TSHRNAAALTA4HTDP1
	SCHEMBL711818	0.83	TSHR (0.48)	ALDH1A1TSHRTAAR1CA1TACR1
	SCHEMBL2734995	0.82	ALOX5 (0.44)	SLC6A2SLC6A4SLC6A3TACR1
	SCHEMBL13279978	0.81	ALDH1A1 (0.50)	ALDH1A1TSHRNAAALTA4HTDP1
	SCHEMBL28289730	0.78	ALDH1A1 (0.45)	ALDH1A1TSHRNAAALTA4HTDP1
	SCHEMBL7689385	0.78	ALDH1A1 (0.47)	ALDH1A1TSHRNAAALTA4HTDP1
	SCHEMBL14130984	0.77	GAA (0.41)	ALDH1A1TDP1L3MBTL1OPRM1
	SCHEMBL2796691	0.76	TSHR (0.41)	ALDH1A1TSHRNAAALTA4HCHRM3
	Ammonia Solution, Strong SCHEMBL28855406	0.76	ALDH1A1 (0.46)	ALDH1A1TSHRNAAALTA4HTDP1
	SCHEMBL1900502	0.76	ALDH1A1 (0.46)	ALDH1A1TSHRNAAALTA4HTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.