Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22142216 | 0.80 | TSHR (0.36) | TSHR | |
| SCHEMBL7956491 | 0.77 | ALDH1A1 (0.35) | TSHR | |
| SCHEMBL12435678 | 0.74 | TSHR (0.38) | TSHR | |
| SCHEMBL18897307 | 0.74 | TSHR (0.32) | TSHR | |
| SCHEMBL11989570 | 0.74 | TSHR (0.38) | TSHR | |
| SCHEMBL24997161 | 0.72 | — | — | |
| SCHEMBL19363057 | 0.72 | — | — | |
| SCHEMBL17628559 | 0.71 | TSHR (0.35) | TSHR | |
| SCHEMBL28638472 | 0.70 | — | — | |
| SCHEMBL29531131 | 0.69 | ALDH1A1 (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6504024-B2 | Useful as substrates for polymerase enzymes; used in preparing fluorescently-labeled nucleotides useful as substrates for thermostable polymerases | PE CORPORATION (NY) | 2003-01-07 | — | — | US | disclosed |
| US-20020045180-A1 | Propargylethoxyamino nucleotide primer extensions | THE PERKIN-ELMER CORPORATION | 2002-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045180-A1 | Propargylethoxyamino nucleotide primer extensions | RNGTT, NUDT1, PNP | TSHR 2886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.