Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.78 |
| ▸ | HTT | P42858 | 1/20 | 0.78 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.65 |
| ▸ | CSF1R | P07333 | 1/20 | 0.65 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.65 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diaveridine SCHEMBL93896 | 0.88 | DHFR (1.00) | DHFRHTTNTRK1CSF1RNTRK3 | |
| Diaveridine SCHEMBL29527560 | 0.88 | DHFR (1.00) | DHFRHTTNTRK1CSF1RNTRK3 | |
| SCHEMBL9657245 | 0.84 | DHFR (0.78) | DHFRHTTNTRK1CSF1RNTRK3 | |
| SCHEMBL9830386 | 0.84 | DHFR (0.82) | DHFRHTTNTRK1CSF1RNTRK3 | |
| SCHEMBL5943361 | 0.83 | DHFR (0.82) | DHFR | |
| Hydrochloric Acid SCHEMBL11385904 | 0.83 | DHFR (0.76) | DHFRHTTNTRK1CSF1RNTRK3 | |
| SCHEMBL10488908 | 0.83 | DHFR (0.85) | DHFRHTTNTRK1CSF1RNTRK3 | |
| SCHEMBL11596783 | 0.82 | DHFR (0.77) | DHFRHTT | |
| SCHEMBL2680692 | 0.82 | DHFR (0.68) | DHFRHTT | |
| SCHEMBL9654048 | 0.82 | DHFR (0.78) | DHFRHTTNTRK1CSF1RNTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1136198-C | Novel benzyl pyrimidines | ��������ҩ�ɷ�����˾ | 2004-01-28 | — | — | CN | disclosed |
| EP-0793656-B1 | NOVEL BENZYL PYRIMIDINES | BASILEA PHARMACEUTICA AG (CH) | 2003-03-26 | — | — | EP | disclosed |
| US-5763450-A | BACTERICIDES; TREATMENT OF INFECTIOUS DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |
| CN-1166831-A | Novel benzyl pyrimidines | HOFFMANN LA ROCHE (CH) | 1997-12-03 | — | — | CN | disclosed |
| EP-0793656-A1 | NOVEL BENZYL PYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-09-10 | — | — | EP | disclosed |
| WO-1996016046-A2 | NOVEL BENZYL PYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 1996-05-30 | — | — | WO | disclosed |