Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.30 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | WNT1 | P04628 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7132341 | 0.83 | SLC6A9 (0.34) | MEN1KMT2A | |
| SCHEMBL7126787 | 0.71 | CHRM2 (0.49) | CHRM2CHRM4CHRM1CHRM3TERT | |
| SCHEMBL3470166 | 0.69 | PLA2G10 (0.41) | CHRM2CHRM4CHRM1CHRM3PLA2G10 | |
| SCHEMBL3799622 | 0.69 | PLA2G10 (0.41) | CHRM2CHRM4CHRM1CHRM3PLA2G10 | |
| SCHEMBL27147241 | 0.69 | PLA2G10 (0.41) | CHRM2CHRM4CHRM1CHRM3PLA2G10 | |
| SCHEMBL7132345 | 0.67 | GAA (0.50) | CHRM2CHRM4CHRM1CHRM3TERT | |
| SCHEMBL21063496 | 0.65 | PLA2G10 (0.37) | CHRM2CHRM4CHRM1CHRM3PLA2G10 | |
| SCHEMBL5023981 | 0.65 | CASP3 (0.33) | PLA2G10PLA2G5 | |
| SCHEMBL5029924 | 0.65 | PLA2G10 (0.36) | PLA2G10PLA2G5 | |
| SCHEMBL16749946 | 0.64 | HSD17B10 (0.42) | CHRM2CHRM4CHRM1CHRM3PLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722442-B1 | POLYAZACYCLOALKANES AS DICHELANTS | NYCOMED SALUTAR INC (US) | 2003-01-15 | — | — | EP | disclosed |
| US-5972307-A | ADMINISTERING TO HUMAN OR ANIMAL BODY AN EFFECTIVE AMOUNT OF A DIAGNOSTIC AGENT COMPRISES A METAL CHELATE OF A COMPOUND HAVING TWO MACROCYCLIC CHELANT GROUPS LINKED BY A BRIDGE CONTAINING ESTER OR AMIDE BOND | NYCOMED SALUTAR, INC. (US) | 1999-10-26 | — | — | US | disclosed |
| US-5650133-A | CHELATING AGENTS USEFUL IN DIAGNOSTIC AND THERAPEUTIC COMPOSITIONS | NYCOMED SALUTAR (US) | 1997-07-22 | — | — | US | disclosed |
| WO-1995009848-A2 | POLYAZACYCLOALKANES AS DICHELANTS | NYCOMED SALUTAR, INC. (US) | 1995-04-13 | — | — | WO | disclosed |