Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 7/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 2/20 | 0.39 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | CYBB | P04839 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17919856 | 0.83 | HTR1B (0.51) | HTR1BKCNA3HTR1DSLC6A4HRH1 | |
| SCHEMBL15565685 | 0.80 | HTR1B (0.49) | HTR1BKCNA3HTR1DSLC6A4HRH1 | |
| SCHEMBL9523932 | 0.79 | HTR1B (1.00) | HTR1BKDM4EKCNA3HTR1DSLC6A4 | |
| SCHEMBL30825865 | 0.79 | HTR1B (1.00) | HTR1BKDM4EKCNA3HTR1DSLC6A4 | |
| Hydrochloric Acid SCHEMBL12465902 | 0.77 | NCEH1 (0.49) | HTR1BKDM4EMAPTLMNAMAPK1 | |
| SCHEMBL7415980 | 0.76 | ERN1 (0.40) | HTR1BKDM4EKCNA3HTR1D | |
| SCHEMBL17913768 | 0.76 | MAOB (0.53) | SLC6A4MAPTMAPK1RAB9A | |
| SCHEMBL29576746 | 0.76 | MAOB (0.53) | SLC6A4MAPTMAPK1RAB9A | |
| SCHEMBL7415972 | 0.76 | DAO (0.39) | HTR1BKDM4EKCNA3HTR1DSLC6A4 | |
| SCHEMBL24801284 | 0.74 | CYP2A6 (0.43) | KDM4ESLC6A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030114448-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2003-06-19 | — | — | US | disclosed |
| WO-2002096873-A1 | ISOINDOLE AND ISOQUINOLINE DERIVATIVES AS INHIBITORS OF FACTOR XA | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114448-A1 | Inhibitors of factor Xa | SERPINC1, F11, TFPI | HTR1B 3888/4885KDM4E 3179/4885KCNA3 2630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.