Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 15/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 15/20 | 0.36 |
| ▸ | CDK2 | P24941 | 15/20 | 0.36 |
| ▸ | CDK9 | P50750 | 15/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 8/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 8/20 | 0.35 |
| ▸ | CDK7 | P50613 | 8/20 | 0.35 |
| ▸ | CCNH | P51946 | 8/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7128511 | 0.91 | CCNT1 (0.38) | CCNT1CCNA2CDK2CDK9ALDH1A1 | |
| SCHEMBL7128014 | 0.71 | RAB9A (0.45) | ALDH1A1GAANPC1LMNARAB9A | |
| SCHEMBL7128258 | 0.67 | NPC1 (0.39) | CCNT1CDK2CDK9ALDH1A1GAA | |
| SCHEMBL7125103 | 0.66 | HTR2C (0.45) | NPC1RAB9A | |
| SCHEMBL22510633 | 0.61 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL6756601 | 0.61 | HSP90AA1 (0.38) | ALDH1A1NPC1RAB9AMEN1NFKB1 | |
| SCHEMBL7126625 | 0.61 | EGFR (0.37) | NPC1LMNARAB9AMEN1TP53 | |
| SCHEMBL22114469 | 0.61 | FGFR1 (0.57) | ALDH1A1CYP1A2CYP2D6HPGDHIF1A | |
| SCHEMBL6757787 | 0.60 | ALDH1A1 (0.49) | ALDH1A1MEN1MAPTKMT2ACYP1A2 | |
| SCHEMBL7121283 | 0.60 | ALDH1A1 (0.55) | ALDH1A1GAALMNAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176454-A1 | N-coating heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176454-A1 | N-coating heterocyclic compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, GNE, NIT2 | CCNT1 414/4885CCNA2 105/4885CDK2 195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.