Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | RORC | P51449 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PTPRB | P23467 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5365650 | 0.84 | PPARA (0.58) | PPARAPPARGFFAR1 | |
| SCHEMBL7068949 | 0.82 | NPC1 (0.46) | PPARAPPARGMAPTENPP3ENPP1 | |
| SCHEMBL5365344 | 0.81 | CXCR2 (0.40) | PPARAPPARG | |
| SCHEMBL5661360 | 0.80 | MTNR1A (0.40) | PPARARORC | |
| SCHEMBL4073189 | 0.75 | PPARA (0.71) | PPARAPPARG | |
| SCHEMBL4073200 | 0.75 | PPARA (0.71) | PPARAPPARG | |
| SCHEMBL4080386 | 0.72 | PPARA (0.58) | PPARAPPARGMAPT | |
| SCHEMBL4076821 | 0.72 | PPARA (0.58) | PPARAPPARGMAPT | |
| SCHEMBL5365631 | 0.72 | PPARA (0.49) | PPARAPPARGCA12CA1CA2 | |
| SCHEMBL7127210 | 0.72 | PPARA (0.48) | PPARAPPARGRORCMAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453795-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS | Dr. Reddy's Laboratories Ltd. (IN) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003048116-A2 | ESTERS AND AMIDES AS PPAR-ALPHA AGONISTS ____________ | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-06-12 | — | — | WO | disclosed |