Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 2/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 10/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | YAP1 | P46937 | 1/20 | 0.38 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.38 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5365650 | 0.81 | PPARA (0.58) | PPARAPPARGPPARDALDH1A1LMNA | |
| SCHEMBL7127214 | 0.81 | PPARA (0.41) | PPARAPPARG | |
| SCHEMBL5365631 | 0.80 | PPARA (0.49) | PPARAPPARGPPARDALDH1A1LMNA | |
| SCHEMBL4451916 | 0.80 | PPARA (0.46) | PPARAPPARGPPARDALDH1A1LMNA | |
| SCHEMBL5197222 | 0.79 | BLM (0.50) | PPARAPPARGPPARDALDH1A1LMNA | |
| SCHEMBL3963055 | 0.79 | BLM (0.50) | PPARAPPARGPPARDALDH1A1LMNA | |
| SCHEMBL6396442 | 0.77 | PPARA (0.48) | PPARAPPARGPPARDALDH1A1LMNA | |
| SCHEMBL6387462 | 0.76 | LMNA (0.47) | PPARAPPARGPPARDALDH1A1LMNA | |
| SCHEMBL7777170 | 0.76 | LMNA (0.47) | PPARAPPARGPPARDALDH1A1LMNA | |
| SCHEMBL5367481 | 0.74 | PPARA (0.41) | PPARAPPARGPPARDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309720-B2 | 2-ethoxy-3-phenylpropionic acid derivatives for the treatment of lipid disorders | ASTRAZENECA AB (SE) | 2007-12-18 | — | — | US | disclosed |
| US-20060178432-A1 | 2-Ethoxy-3-phenylpropionic acid derivatives for the treatment of lipid disorders | ASTRAZENECA AB (SE) | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178432-A1 | 2-Ethoxy-3-phenylpropionic acid derivatives for the treatment of lipid disorders | LIPC, PNLIP, CPT1A | CXCR2 4235/4885CXCR1 4610/4885PPARA 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.