Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030793 | 0.83 | HIF1A (0.35) | HIF1ASMN1; SMN2NPC1MAPTCYP1A2 | |
| SCHEMBL7494934 | 0.81 | PARP10 (0.39) | HIF1ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL7464106 | 0.80 | HIF1A (0.35) | HIF1ASMN1; SMN2NPC1MAPTCYP1A2 | |
| SCHEMBL8721309 | 0.79 | HIF1A (0.43) | HIF1A | |
| SCHEMBL7498105 | 0.78 | HIF1A (0.39) | HIF1ASMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL7498151 | 0.78 | HIF1A (0.46) | HIF1AMAPT | |
| SCHEMBL6703061 | 0.77 | HIF1A (0.39) | HIF1AMAPT | |
| SCHEMBL6781009 | 0.77 | HIF1A (0.46) | HIF1ASMN1; SMN2NPC1MAPTCYP1A2 | |
| SCHEMBL6155140 | 0.77 | HIF1A (0.40) | HIF1ASMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL6155148 | 0.77 | HIF1A (0.40) | HIF1ASMN1; SMN2NPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6664422-B1 | Process for the preparation of strobilurin intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 2003-12-16 | — | — | US | disclosed |
| EP-1137627-A1 | PROCESS FOR THE PREPARATION OF STROBILURIN INTERMEDIATES | Bayer Aktiengesellschaft (DE) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034229-A1 | PROCESS FOR THE PREPARATION OF STROBILURIN INTERMEDIATES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-06-15 | — | — | WO | disclosed |