Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PNLIP | P16233 | 3/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470381 | 0.92 | HTR2A (0.34) | HIF1ACYP1A2KMT2ACYP2D6CYP2C19 | |
| SCHEMBL7466206 | 0.90 | MAPK14 (0.36) | HIF1AMEN1KMT2A | |
| SCHEMBL8544631 | 0.86 | MAPK14 (0.37) | HIF1AMAPT | |
| SCHEMBL8540309 | 0.85 | ALDH1A1 (0.36) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7463037 | 0.82 | SMN1; SMN2 (0.38) | HIF1AMEN1KMT2ANPC1MAPT | |
| SCHEMBL7467428 | 0.81 | MAOB (0.43) | HIF1AALDH1A1MAPTPOLB | |
| SCHEMBL7467539 | 0.81 | MAOB (0.46) | HIF1AKMT2AMMP1 | |
| SCHEMBL7495777 | 0.81 | HIF1A (0.44) | HIF1AMEN1KMT2AUTS2RF10 | |
| SCHEMBL7503269 | 0.80 | MAPT (0.38) | HIF1AALDH1A1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL7127230 | 0.80 | HIF1A (0.46) | HIF1ACYP1A2MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865424-B1 | PESTICIDES | BAYER AG (DE) | 2002-09-18 | — | — | EP | disclosed |
| EP-0865424-A1 | PESTICIDES | Novartis AG (CH) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020809-A1 | PESTICIDES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |