Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | ACR | P10323 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494028 | 0.91 | MAPK14 (0.39) | HIF1AMAPK14CHEK2BTKGCGR | |
| SCHEMBL8721309 | 0.88 | HIF1A (0.43) | HIF1ARXFP1GAA | |
| SCHEMBL8544631 | 0.86 | MAPK14 (0.37) | HIF1AMAPK14CHEK2BTKGCGR | |
| SCHEMBL7467262 | 0.82 | MAPK14 (0.39) | HIF1AMAPK14CHEK2BTKGCGR | |
| SCHEMBL6060789 | 0.81 | HIF1A (0.47) | HIF1ARXFP1MAPTGAA | |
| SCHEMBL7500249 | 0.80 | HIF1A (0.49) | HIF1AMAPT | |
| SCHEMBL7498154 | 0.79 | HIF1A (0.57) | HIF1AMAPK14CHEK2GCGRRXFP1 | |
| SCHEMBL7466206 | 0.78 | MAPK14 (0.36) | HIF1AMAPK14RXFP1 | |
| SCHEMBL7127230 | 0.78 | HIF1A (0.46) | HIF1AMAPT | |
| SCHEMBL8190761 | 0.77 | MAPK14 (0.36) | HIF1AMAPK14CHEK2BTKGCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420423-B1 | PESTICIDE FOR USE ON CEREALS, BEETS, FRUITS, BERRIES, AND BEANS; KILLS MITES, INSECTS, TERMITES, LICE, FLEAS, AND FUNGUS; TOLERATED WELL BE ANIMALS, PLANTS, AND FISH | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-16 | — | — | US | disclosed |
| EP-1207152-A2 | Pesticides | Bayer Aktiengesellschaft (DE) | 2002-05-22 | — | — | EP | disclosed |
| US-5985921-A | OXIDATION AND HYDROGENATION OF COMPOUNDS TO FORM INSECTICIDES AS AGROCHEMICALS | NOVARTIS CORPORATION (US) | 1999-11-16 | — | — | US | disclosed |
| EP-0865424-A1 | PESTICIDES | Novartis AG (CH) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020809-A1 | PESTICIDES | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |