Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | CTSV | O60911 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27570117 | 0.92 | CYP2D6 (0.33) | KMT2ACYP2D6GRM2GRM3LMNA | |
| SCHEMBL14590794 | 0.90 | KMT2A (0.34) | KMT2ACYP2D6LMNANR1I2ABCB11 | |
| SCHEMBL5338552 | 0.89 | KMT2A (0.33) | KMT2ACYP2D6LMNANR1I2ABCB11 | |
| SCHEMBL886987 | 0.89 | KMT2A (0.36) | KMT2ACYP2D6LMNANR1I2ABCB11 | |
| SCHEMBL5336900 | 0.88 | BCHE (0.35) | KMT2ACYP2D6LMNANR1I2ABCB11 | |
| SCHEMBL5340543 | 0.88 | CYP3A4 (0.34) | KMT2ACYP2D6LMNANR1I2ABCB11 | |
| SCHEMBL14590798 | 0.87 | BCHE (0.39) | KMT2AKCNH2 | |
| SCHEMBL5346730 | 0.86 | TSHR (0.34) | KMT2ACYP2D6LMNANR1I2ABCB11 | |
| SCHEMBL5348395 | 0.86 | BCHE (0.36) | KMT2ACYP2D6LMNACTSVCTSL | |
| SCHEMBL5341930 | 0.86 | CHRNB2 (0.34) | KMT2ACYP2D6LMNANR1I2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065184-A1 | 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | CIBA SPECIALTY CHEMICALS CORP. | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065184-A1 | 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides | ALKBH2, NFE2L2, DPYSL2 | KMT2A 1595/4885CYP2D6 182/4885GRM2 1880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.