Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834412 | 0.86 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL7128527 | 0.85 | PARP14 (0.38) | KDM4EALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL6830741 | 0.77 | ALDH1A1 (0.47) | KDM4EALDH1A1HSD17B10GAALMNA | |
| SCHEMBL6833726 | 0.76 | PARP14 (0.45) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL6834299 | 0.76 | MEN1 (0.56) | KDM4EALDH1A1HSD17B10GAALMNA | |
| SCHEMBL6833087 | 0.75 | MEN1 (0.44) | KDM4EALDH1A1HSD17B10GAALMNA | |
| SCHEMBL6711390 | 0.74 | TP53 (0.42) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL6834350 | 0.74 | ALDH1A1 (0.50) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL6709308 | 0.73 | TP53 (0.41) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL6834504 | 0.73 | LMNA (0.47) | KDM4EALDH1A1LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |