Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834072 | 0.86 | ALDH1A1 (0.41) | PARP14LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL7127481 | 0.85 | KDM4E (0.47) | LMNASMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL6834504 | 0.78 | LMNA (0.47) | PARP14LMNASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6833157 | 0.78 | PARP14 (0.42) | PARP14LMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL6833683 | 0.78 | NR1H4 (0.48) | ALDH1A1NLRP3 | |
| SCHEMBL6833766 | 0.77 | PARP14 (0.43) | PARP14LMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL6835671 | 0.77 | LMNA (0.39) | PARP14LMNAMAPTMAPK1 | |
| SCHEMBL6834079 | 0.77 | NHERF1 (0.44) | PARP14LMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL6834134 | 0.77 | IDO1 (0.43) | PARP14LMNAALDH1A1KDM4EIDO1 | |
| SCHEMBL7124935 | 0.77 | CNR1 (0.32) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |