Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27752562 | 0.89 | MAPT (0.54) | ALDH1A1TP53TDP1LMNANPC1 | |
| SCHEMBL973720 | 0.83 | CA1 (0.47) | ALDH1A1TP53TDP1LMNASMN1; SMN2 | |
| SCHEMBL22588999 | 0.79 | LMNA (0.62) | ALDH1A1TP53LMNASMN1; SMN2NPC1 | |
| SCHEMBL16897446 | 0.78 | PKM (0.50) | ALDH1A1TDP1LMNASMN1; SMN2MAPT | |
| SCHEMBL11794766 | 0.78 | F2 (0.49) | ALDH1A1LMNASMN1; SMN2MAPTPOLB | |
| SCHEMBL27752550 | 0.78 | ITGAV (0.48) | ALDH1A1TP53TDP1LMNANPC1 | |
| SCHEMBL8768499 | 0.78 | ALDH1A1 (0.63) | ALDH1A1TP53TDP1LMNASMN1; SMN2 | |
| SCHEMBL11831137 | 0.76 | PBRM1 (0.50) | ALDH1A1TDP1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL11798964 | 0.76 | CA1 (0.43) | ALDH1A1TDP1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL25205427 | 0.76 | ALDH1A1 (0.60) | ALDH1A1TP53TDP1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6664021-B1 | Acid generator and silicon-containing polyimide ester precursor comprising partially esterified silicon-containing polyamic ester; radiating with light | CHISSO CORPORATION (JP) | 2003-12-16 | — | — | US | disclosed |