Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129737 | 0.94 | GAA (0.63) | GAAHSD17B10ALOX15TSHRALDH1A1 | |
| SCHEMBL5872643 | 0.91 | GAA (0.65) | GAAHSD17B10ALOX15TSHRALDH1A1 | |
| SCHEMBL9643768 | 0.88 | GAA (0.50) | GAAHSD17B10ALOX15TSHRALDH1A1 | |
| SCHEMBL7913433 | 0.87 | GAA (0.50) | GAAHSD17B10ALOX15TSHRALDH1A1 | |
| SCHEMBL27650122 | 0.86 | GAA (0.48) | GAAHSD17B10ALOX15TSHRALDH1A1 | |
| SCHEMBL22882728 | 0.86 | GAA (0.48) | GAAHSD17B10ALOX15TSHRALDH1A1 | |
| SCHEMBL15499763 | 0.85 | BLM (0.49) | GAAHSD17B10ALOX15TSHRALDH1A1 | |
| SCHEMBL14752935 | 0.85 | BLM (0.49) | GAAHSD17B10ALOX15TSHRALDH1A1 | |
| SCHEMBL6848102 | 0.84 | HSD17B10 (0.64) | GAAHSD17B10ALOX15TSHRALDH1A1 | |
| SCHEMBL173508 | 0.84 | HSD17B10 (0.64) | GAAHSD17B10ALOX15TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722442-B1 | POLYAZACYCLOALKANES AS DICHELANTS | NYCOMED SALUTAR INC (US) | 2003-01-15 | — | — | EP | disclosed |
| US-5972307-A | ADMINISTERING TO HUMAN OR ANIMAL BODY AN EFFECTIVE AMOUNT OF A DIAGNOSTIC AGENT COMPRISES A METAL CHELATE OF A COMPOUND HAVING TWO MACROCYCLIC CHELANT GROUPS LINKED BY A BRIDGE CONTAINING ESTER OR AMIDE BOND | NYCOMED SALUTAR, INC. (US) | 1999-10-26 | — | — | US | disclosed |
| US-5650133-A | CHELATING AGENTS USEFUL IN DIAGNOSTIC AND THERAPEUTIC COMPOSITIONS | NYCOMED SALUTAR (US) | 1997-07-22 | — | — | US | disclosed |
| WO-1995009848-A2 | POLYAZACYCLOALKANES AS DICHELANTS | NYCOMED SALUTAR, INC. (US) | 1995-04-13 | — | — | WO | disclosed |