Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | CD38 | P28907 | 1/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497144 | 0.81 | LMNA (0.42) | KDM4EHSD17B10NR4A2NR4A1NR4A3 | |
| SCHEMBL6489796 | 0.75 | MAPT (0.42) | HDAC1HDAC8HDAC6LMNAMAPT | |
| SCHEMBL7064560 | 0.74 | HRH3 (0.39) | KDM4EHSD17B10NR4A2CD38HDAC1 | |
| SCHEMBL7196721 | 0.73 | PPARG (0.46) | NR4A2NR4A1NR4A3FABP3FABP4 | |
| SCHEMBL7129648 | 0.73 | LMNA (0.37) | KDM4EHSD17B10NR4A2NR4A1NR4A3 | |
| SCHEMBL6487724 | 0.73 | HDAC1 (0.39) | CD38HDAC1HDAC8HDAC6POLB | |
| SCHEMBL7064566 | 0.71 | HDAC1 (0.39) | KDM4EHSD17B10CD38HDAC1HDAC8 | |
| SCHEMBL7127785 | 0.71 | LMNA (0.36) | KDM4EHSD17B10NR4A2CD38HDAC1 | |
| SCHEMBL6301593 | 0.70 | HDAC1 (0.54) | KDM4EHDAC1HDAC8HDAC6POLB | |
| SCHEMBL7129639 | 0.70 | HDAC1 (0.38) | KDM4EHSD17B10NR4A2CD38HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |