Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7070085 | 0.93 | MAPT (0.36) | LMNAKDM4EGAAPPARAPPARD | |
| SCHEMBL7065211 | 0.89 | IDO1 (0.39) | HRH3HDAC1HDAC8HDAC6KDM4E | |
| SCHEMBL7068046 | 0.87 | HDAC1 (0.39) | HRH3LMNAHDAC1HDAC8HDAC6 | |
| SCHEMBL7160232 | 0.81 | HDAC1 (0.42) | HRH3LMNAHDAC1HDAC8HDAC6 | |
| SCHEMBL6489796 | 0.80 | MAPT (0.42) | HRH3LMNAHDAC1HDAC8HDAC6 | |
| SCHEMBL7064566 | 0.80 | HDAC1 (0.39) | LMNAHDAC1HDAC8HDAC6KDM4E | |
| SCHEMBL7129648 | 0.80 | LMNA (0.37) | HRH3LMNAHDAC1HDAC8HDAC6 | |
| SCHEMBL7068552 | 0.78 | KMT2A (0.43) | LMNAL3MBTL1MAPK1 | |
| SCHEMBL6487724 | 0.78 | HDAC1 (0.39) | HRH3LMNAHDAC1HDAC8HDAC6 | |
| SCHEMBL7129639 | 0.77 | HDAC1 (0.38) | HRH3LMNAHDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |