Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7064560 | 0.73 | HRH3 (0.39) | LMNAHDAC1HDAC8HDAC6KDM4E | |
| SCHEMBL6489796 | 0.71 | MAPT (0.42) | LMNAHDAC1HDAC8HDAC6TDP1 | |
| SCHEMBL7129648 | 0.71 | LMNA (0.37) | LMNAHDAC1HDAC8HDAC6KDM4E | |
| SCHEMBL6497144 | 0.71 | LMNA (0.42) | LMNAKDM4EHSD17B10NR4A2CD38 | |
| SCHEMBL7127792 | 0.71 | KDM4E (0.44) | LMNAHDAC1HDAC8HDAC6KDM4E | |
| SCHEMBL7064566 | 0.70 | HDAC1 (0.39) | LMNAHDAC1HDAC8HDAC6KDM4E | |
| SCHEMBL6487724 | 0.70 | HDAC1 (0.39) | LMNAHDAC1HDAC8HDAC6ADORA3 | |
| SCHEMBL7129639 | 0.69 | HDAC1 (0.38) | LMNAHDAC1HDAC8HDAC6KDM4E | |
| SCHEMBL6301593 | 0.67 | HDAC1 (0.54) | LMNAHDAC1HDAC8HDAC6KDM4E | |
| SCHEMBL6496310 | 0.67 | THRB (0.41) | KDM4EL3MBTL1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |