Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 2/20 | 0.38 |
| ▸ | FLT4 | P35916 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 2/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830680 | 0.81 | FAAH (0.49) | FAAHXDHSLC22A12FLT1FLT4 | |
| SCHEMBL29268996 | 0.78 | FAAH (0.64) | FAAHXDHSLC22A12FLT1FLT4 | |
| Lithium SCHEMBL30975829 | 0.78 | FAAH (0.64) | FAAHXDHSLC22A12FLT1FLT4 | |
| SCHEMBL6833423 | 0.72 | FAAH (0.52) | FAAHXDHSLC22A12FLT1FLT4 | |
| Lithium Ion SCHEMBL22557575 | 0.72 | FAAH (0.59) | FAAHXDHSLC22A12FLT1FLT4 | |
| SCHEMBL6834004 | 0.69 | TUBB4A (0.44) | FAAHHDAC1HDAC6KMT2A | |
| SCHEMBL29269012 | 0.69 | HDAC1 (0.55) | FAAHHDAC1HDAC6CES1NPC1 | |
| Lithium SCHEMBL30975809 | 0.69 | HDAC1 (0.55) | FAAHHDAC1HDAC6CES1NPC1 | |
| SCHEMBL6926835 | 0.68 | FAAH (0.57) | FAAHFLT1FLT4KDRCES1 | |
| SCHEMBL31223841 | 0.67 | XDH (0.55) | FAAHXDHSLC22A12PRKDCNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |