Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129871 | 0.95 | SLC6A3 (0.34) | SIGMAR1 | |
| SCHEMBL7128351 | 0.92 | HRH3 (0.33) | SIGMAR1HRH3 | |
| SCHEMBL7126837 | 0.81 | SLC6A2 (0.31) | — | |
| SCHEMBL7127976 | 0.77 | SLC6A2 (0.35) | — | |
| SCHEMBL6079957 | 0.77 | SLC6A2 (0.34) | — | |
| SCHEMBL27980514 | 0.75 | SIGMAR1 (0.34) | SIGMAR1 | |
| SCHEMBL4374285 | 0.73 | HRH3 (0.45) | HRH3 | |
| SCHEMBL7123110 | 0.72 | — | — | |
| SCHEMBL6968694 | 0.72 | SLC6A3 (0.40) | — | |
| SCHEMBL4628866 | 0.70 | SLC6A3 (0.39) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311500-A2 | INDOLE, AZAINDOLE AND INDAZOLE DERIVATIVES HAVING VEGF INHIBITING ACTIVITY | AstraZeneca AB (SE) | 2003-05-21 | — | — | EP | disclosed |
| EP-1309587-A1 | CINNOLINE COMPOUNDS | AstraZeneca AB (SE) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002016348-A1 | ANTIANGIOGENIC BICYCLIC DERIVATIVES | ASTRAZENECA AB (SE) | 2002-02-28 | — | — | WO | disclosed |
| WO-2002012228-A1 | CINNOLINE COMPOUNDS | ASTRAZENECA AB (SE) | 2002-02-14 | — | — | WO | disclosed |
| WO-2002012227-A2 | INDOLE, AZAINDOLE AND INDAZOLE DERIVATIVES HAVING VEGF INHIBITING ACTIVITY | ASTRAZENECA AB (SE) | 2002-02-14 | — | — | WO | disclosed |