Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.32 |
| ▸ | CASP2 | P42575 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | F13A1 | P00488 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | CA5A | P35218 | 2/20 | 0.31 |
| ▸ | THPO | P40225 | 2/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8362130 | 1.00 | POLB (0.33) | POLBPAOXCASP2CA12F13A1 | |
| SCHEMBL8476517 | 0.94 | PAOX (0.38) | POLBPAOXCASP2CA12F13A1 | |
| SCHEMBL8476513 | 0.94 | PAOX (0.38) | POLBPAOXCASP2CA12F13A1 | |
| SCHEMBL8476697 | 0.92 | PAOX (0.41) | POLBPAOXCA12F13A1CA2 | |
| SCHEMBL8476699 | 0.92 | PAOX (0.41) | POLBPAOXCA12F13A1CA2 | |
| SCHEMBL7128026 | 0.88 | POLB (0.35) | POLBTSHR | |
| Upenazime SCHEMBL1477985 | 0.87 | POLB (0.37) | POLBTSHR | |
| SCHEMBL8693325 | 0.87 | POLB (0.37) | POLBTSHR | |
| SCHEMBL8693335 | 0.87 | POLB (0.37) | POLBTSHR | |
| SCHEMBL15144439 | 0.85 | POLB (0.36) | POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5993774-A | Metal-oxime chelates for use as radiopharmaceutical agents | AMERSHAM INTERNATIONAL PLC (GB) | 1999-11-30 | — | — | US | disclosed |
| EP-0663900-B1 | METAL-OXIME CHELATES FOR USE AS RADIOPHARMACEUTICAL AGENTS | NYCOMED AMERSHAM PLC (GB) | 1999-09-22 | — | — | EP | disclosed |
| EP-0663900-A1 | METAL-OXIME CHELATES FOR USE AS RADIOPHARMACEUTICAL AGENTS | AMERSHAM INTERNATIONAL plc (GB) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994008949-A2 | METAL-OXIME CHELATES FOR USE AS RADIOPHARMACEUTICAL AGENTS | AMERSHAM INTERNATIONAL PLC (GB) | 1994-04-28 | — | — | WO | disclosed |