Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | F13A1 | P00488 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476697 | 1.00 | PAOX (0.41) | PAOXMAOAMAOBCA12F13A1 | |
| SCHEMBL8476513 | 0.98 | PAOX (0.38) | PAOXCA12F13A1CA1CA2 | |
| SCHEMBL8476517 | 0.98 | PAOX (0.38) | PAOXCA12F13A1CA1CA2 | |
| SCHEMBL8362130 | 0.92 | POLB (0.33) | PAOXCA12F13A1CA1CA2 | |
| SCHEMBL8362134 | 0.92 | POLB (0.33) | PAOXCA12F13A1CA1CA2 | |
| SCHEMBL15135657 | 0.90 | POLB (0.36) | TSHRPOLBSMN1; SMN2 | |
| SCHEMBL15144439 | 0.90 | POLB (0.36) | TSHRPOLBSMN1; SMN2 | |
| Upenazime SCHEMBL1477985 | 0.88 | POLB (0.37) | TSHRPOLBSMN1; SMN2 | |
| SCHEMBL7128026 | 0.84 | POLB (0.35) | TSHRPOLBSMN1; SMN2 | |
| SCHEMBL8693335 | 0.84 | POLB (0.37) | TSHRPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5997843-A | TECHNETIUM-99M | AMERSHAM INTERNATIONAL PLC (GB) | 1999-12-07 | — | — | US | disclosed |
| EP-0712315-A1 | RADIOMETAL COMPLEXES THAT LOCALISE IN HYPOXIC TISSUE | AMERSHAM INTERNATIONAL plc (GB) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995004552-A2 | RADIOMETAL COMPLEXES THAT LOCALISE IN HYPOXIC TISSUE | AMERSHAM INTERNATIONAL PLC (GB) | 1995-02-16 | — | — | WO | disclosed |