Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL829599 | 1.00 | DNM1 (0.64) | DNM1RECQLTSHRGLAHPGD | |
| SCHEMBL3780740 | 0.98 | DNM1 (0.68) | DNM1RECQLTSHRGLAHPGD | |
| SCHEMBL832250 | 0.98 | DNM1 (0.68) | DNM1RECQLTSHRGLAHPGD | |
| SCHEMBL3780468 | 0.91 | DNM1 (0.52) | DNM1RECQLTSHRGLAHPGD | |
| Sulfuric Acid SCHEMBL10530606 | 0.91 | DNM1 (0.71) | DNM1RECQLTSHRGLAHPGD | |
| Sulfuric Acid SCHEMBL7175400 | 0.91 | DNM1 (0.64) | DNM1RECQLTSHRGLAHPGD | |
| Sulfuric Acid SCHEMBL7558712 | 0.91 | DNM1 (0.64) | DNM1RECQLTSHRGLAHPGD | |
| SCHEMBL15401788 | 0.90 | DNM1 (0.55) | DNM1RECQLTSHRGLAHPGD | |
| SCHEMBL306924 | 0.90 | DNM1 (0.55) | DNM1RECQLTSHRGLAHPGD | |
| Sulfuric Acid SCHEMBL23089049 | 0.88 | DNM1 (0.61) | DNM1RECQLTSHRGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003051894-A1 | PREPARATION OF IONIC LIQUIDS | CYTEC CANADA INC. (CA) | 2003-06-26 | — | — | WO | claimed |
| WO-2003051894-A1 | PREPARATION OF IONIC LIQUIDS | CYTEC CANADA INC. (CA) | 2003-06-26 | — | — | WO | disclosed |