Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.50 |
| ▸ | NOS1 | P29475 | 4/20 | 0.48 |
| ▸ | NOS3 | P29474 | 3/20 | 0.46 |
| ▸ | NOS2 | P35228 | 3/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7130674 | 0.78 | NOS1 (0.38) | EPHX2NOS1NOS3NOS2 | |
| SCHEMBL7128085 | 0.78 | EPHX2 (0.53) | EPHX2BACE1BACE2 | |
| SCHEMBL7984247 | 0.77 | NOS1 (0.48) | NOS1NOS3NOS2 | |
| SCHEMBL7115895 | 0.71 | EPHX2 (0.71) | EPHX2BACE1BACE2 | |
| SCHEMBL7084932 | 0.71 | NOS1 (0.61) | NOS1NOS3NOS2 | |
| SCHEMBL9037289 | 0.69 | KCNK3 (0.67) | NOS1NOS3NOS2 | |
| SCHEMBL4741893 | 0.69 | EPHX2 (0.71) | EPHX2BACE1BACE2 | |
| SCHEMBL14804986 | 0.68 | EPHX2 (0.81) | EPHX2BACE1BACE2 | |
| SCHEMBL6280369 | 0.68 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL6923001 | 0.68 | EPHX2 (0.69) | EPHX2BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176454-A1 | N-coating heterocyclic compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176454-A1 | N-coating heterocyclic compounds | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, GNE, NIT2 | EPHX2 354/4885NOS1 417/4885NOS3 538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.