Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 5/20 | 0.48 |
| ▸ | NOS3 | P29474 | 4/20 | 0.46 |
| ▸ | NOS2 | P35228 | 4/20 | 0.46 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7128091 | 0.77 | EPHX2 (0.50) | NOS1NOS3NOS2 | |
| SCHEMBL7984241 | 0.75 | HIF1A (0.38) | — | |
| SCHEMBL6280369 | 0.68 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL4396067 | 0.67 | NOS1 (0.68) | NOS1NOS3NOS2QRFPR | |
| Iodide SCHEMBL9053048 | 0.67 | NOS1 (0.96) | NOS1NOS3NOS2 | |
| SCHEMBL6984671 | 0.66 | NOS1 (0.66) | NOS1NOS3NOS2QRFPR | |
| Iodide SCHEMBL4402647 | 0.66 | NOS1 (0.66) | NOS1NOS3NOS2QRFPR | |
| SCHEMBL6984675 | 0.66 | NOS1 (0.66) | NOS1NOS3NOS2QRFPR | |
| SCHEMBL4628022 | 0.66 | NOS1 (0.57) | NOS1NOS3NOS2 | |
| SCHEMBL4628020 | 0.66 | NOS1 (0.57) | NOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087845-A2 | N-CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR USE AS 5-HT ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-22 | — | — | WO | disclosed |