SCHEMBL7128267

Cc1cc(-c2ccc(C(C)(C)C)cc2)cc(-c2ccc(C(C)(C)C)cc2)c1C(COP(O)O)c1c(C)cc(-c2ccc(C(C)(C)C)cc2)cc1-c1ccc(C(C)(C)C)cc1

nearest known ligand 0.35

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	RXRB	P28702	6/20	0.35

▸	RXRA	P19793	5/20	0.35

▸	AKR1C2	P52895	2/20	0.33

▸	AKR1C3	P42330	1/20	0.33

▸	RXRG	P48443	3/20	0.33

▸	AKR1C1	Q04828	1/20	0.33

▸	GPR84	Q9NQS5	1/20	0.32

▸	FFAR1	O14842	1/20	0.32

▸	KIF11	P52732	2/20	0.31

▸	DHODH	Q02127	1/20	0.31

▸	ALDH1A1	P00352	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29421164	0.74	ALDH1A1 (0.35)	RXRBRXRARXRGALDH1A1
SCHEMBL39015	0.74	ALDH1A1 (0.35)	RXRBRXRARXRGALDH1A1
SCHEMBL5455460	0.73	ALDH1A1 (0.34)	RXRBRXRARXRGALDH1A1
SCHEMBL2264850	0.69	SMN1; SMN2 (0.38)	ALDH1A1
SCHEMBL8913292	0.68	CYP1A2 (0.31)	ALDH1A1
SCHEMBL30967286	0.66	CYP2C19 (0.38)	ALDH1A1
SCHEMBL30100374	0.65	KDM4E (0.33)	ALDH1A1
SCHEMBL18421489	0.65	—	—
SCHEMBL1100311	0.65	LMNA (0.38)	ALDH1A1
SCHEMBL8919526	0.64	RXRA (0.31)	RXRBRXRARXRGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1024165-B1	STABILIZER COMPOSITION FOR ORGANIC POLYMERIC MATERIALS CONTAINING 6-HYDROXYCHROMAN COMPOUNDS AND ORGANIC POLYMERIC MATERIAL COMPOSITIONS	API CORP (JP)	2003-07-09	—	—	EP	disclosed