Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD5 | P21918 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010381 | 0.83 | ESR1 (0.48) | OPRM1OPRK1KDM4EDRD2DRD3 | |
| SCHEMBL7130765 | 0.76 | OPRK1 (0.48) | OPRM1OPRD1OPRK1KDM4EESR1 | |
| SCHEMBL1204926 | 0.76 | DRD2 (0.65) | OPRM1OPRD1OPRK1KDM4EDRD2 | |
| SCHEMBL7125488 | 0.74 | OPRK1 (0.42) | OPRM1OPRD1OPRK1KDM4EDRD2 | |
| SCHEMBL14032395 | 0.72 | ESR1 (0.58) | CYP3A4ESR1ESR2MEN1ALDH1A1 | |
| SCHEMBL7011495 | 0.72 | ESR1 (0.58) | CYP3A4ESR1ESR2MEN1ALDH1A1 | |
| SCHEMBL6143092 | 0.70 | ESR1 (0.54) | OPRM1OPRD1OPRK1KDM4EDRD2 | |
| SCHEMBL7078443 | 0.69 | DRD2 (0.56) | OPRM1OPRD1OPRK1KDM4EDRD2 | |
| SCHEMBL7717163 | 0.69 | TSHR (0.39) | TSHRALDH1A1CYP1A2 | |
| SCHEMBL27534382 | 0.69 | ESR1 (0.52) | KDM4ECYP3A4HIF1AHSD17B10ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003043973-A2 | AMINE PHENOLIC COMPOUNDS AND THEIR USE AS HARDENERS AND/OR ACCELERATORS IN EPOXY COATINGS | SIGMA COATINGS B.V. (NL) | 2003-05-30 | — | — | WO | disclosed |
| EP-1314716-A1 | Amine phenolic compounds and their use as hardener and/or accelerators in epoxy coatings | SIGMA COATINGS B.V. (NL) | 2003-05-28 | — | — | EP | disclosed |