Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 8/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7128508 | 0.76 | OPRM1 (0.47) | OPRK1OPRM1OPRD1KDM4EALDH1A1 | |
| SCHEMBL1204926 | 0.73 | DRD2 (0.65) | OPRK1OPRM1OPRD1KDM4ESLC6A2 | |
| SCHEMBL10662260 | 0.71 | TAAR1 (0.63) | OPRK1OPRD1KDM4ETAAR1SLC6A2 | |
| SCHEMBL6143092 | 0.71 | ESR1 (0.54) | OPRK1OPRM1OPRD1KDM4ETAAR1 | |
| SCHEMBL896162 | 0.67 | SLC6A2 (0.63) | OPRK1OPRM1KDM4ETAAR1SLC6A2 | |
| SCHEMBL44507 | 0.67 | SLC6A2 (0.63) | OPRK1OPRM1KDM4ETAAR1SLC6A2 | |
| SCHEMBL895572 | 0.67 | SLC6A2 (0.63) | OPRK1OPRM1KDM4ETAAR1SLC6A2 | |
| SCHEMBL7078443 | 0.67 | DRD2 (0.56) | OPRK1OPRM1OPRD1KDM4ESLC6A2 | |
| SCHEMBL104626 | 0.67 | ESR1 (0.59) | OPRK1OPRM1KDM4ETAAR1SLC6A2 | |
| Hordenine SCHEMBL19896488 | 0.67 | HRH3 (0.67) | KDM4ETAAR1SLC6A2ALDH1A1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003043973-A2 | AMINE PHENOLIC COMPOUNDS AND THEIR USE AS HARDENERS AND/OR ACCELERATORS IN EPOXY COATINGS | SIGMA COATINGS B.V. (NL) | 2003-05-30 | — | — | WO | disclosed |
| EP-1314716-A1 | Amine phenolic compounds and their use as hardener and/or accelerators in epoxy coatings | SIGMA COATINGS B.V. (NL) | 2003-05-28 | — | — | EP | disclosed |