SCHEMBL7128516

SCHEMBL7128516

CCCC(CCC)OC(=O)c1ccc(OCc2ccccc2)cc1F

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.51
MAOA P21397 1/20 0.49
PARP10 Q53GL7 2/20 0.46
PARP15 Q460N3 1/20 0.46
MRGPRX4 Q96LA9 1/20 0.45
NOX1 Q9Y5S8 1/20 0.45
ALDH1A1 P00352 1/20 0.44
FFAR1 O14842 2/20 0.43
PPARD Q03181 2/20 0.43
MEN1 O00255 1/20 0.43
HSP90AA1 P07900 1/20 0.43
KMT2A Q03164 1/20 0.43
CTSV O60911 1/20 0.43
CTSL P07711 1/20 0.43
PARP14 Q460N5 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7167903 0.84 ALDH1A1 (0.57) MAOBMAOAPARP10PARP15NOX1
SCHEMBL7167908 0.84 ALDH1A1 (0.57) MAOBMAOAPARP10PARP15NOX1
SCHEMBL176858 0.81 MAOB (0.59) MAOBMAOAPARP10PARP15MRGPRX4
SCHEMBL9129155 0.81 CTRC (0.45) MAOBMAOA
SCHEMBL2989798 0.80 MAOB (0.57) MAOBMAOAPARP10PARP15MRGPRX4
SCHEMBL2997270 0.79 MAOB (0.62) MAOBMAOAPARP10PARP15MRGPRX4
SCHEMBL7130383 0.79 CA12 (0.45)
SCHEMBL1555449 0.79 MAOB (0.79) MAOBMAOAPARP10PARP15
SCHEMBL27683488 0.78 MAOB (0.61) MAOBMAOAPARP10PARP15MRGPRX4
Hydrochloric Acid SCHEMBL9015457 0.78 MAOB (0.61) MAOBMAOAPARP10PARP15MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6666989-B1 Electrical and electro-optic apparatus comprising spaced glass panels having polyethers and electrodes on the interior surfaces, used as detectors, screens and in nonlinear optical apparatus QINETIQ LIMITED (GB) 2003-12-23 US disclosed
EP-1060226-A1 LIQUID CRYSTAL POLYMER DEVICES AND MATERIALS THE SECRETARY OF STATE FOR DEFENCE (GB) 2000-12-20 EP disclosed
WO-1999043763-A1 LIQUID CRYSTAL POLYMER DEVICES AND MATERIALS THE SECRETARY OF STATE FOR DEFENCE (GB) 1999-09-02 WO disclosed