Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7131067 | 1.00 | MEN1 (0.39) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL7131070 | 0.94 | MEN1 (0.36) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL7120797 | 0.82 | ALDH1A1 (0.42) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL7131314 | 0.82 | ALDH1A1 (0.42) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL7133628 | 0.82 | SMN1; SMN2 (0.42) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL7129200 | 0.76 | ALDH1A1 (0.40) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7801826 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL6559249 | 0.75 | NPSR1 (0.47) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL7797401 | 0.74 | MEN1 (0.49) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL677902 | 0.74 | MEN1 (0.34) | MEN1KMT2AMAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670499-B1 | Bis-Methacryloyloxy-adamantanedicarboxylate derivatives; raw materials for dental materials and lenses; transparency, luster, hardness, water resistance | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-12-30 | — | — | US | disclosed |
| EP-1164125-A1 | ADAMANTANE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Daicel Chemical Industries, Ltd. (JP) | 2001-12-19 | — | — | EP | disclosed |