SCHEMBL7120797

SCHEMBL7120797

C=C(C)C(=O)OCC(COC(=O)C(=C)C)(COC(=O)C(=C)C)COC(=O)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.42
MAPT P10636 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
PRKCA P17252 1/20 0.41
CYP17A1 P05093 3/20 0.40
CYP19A1 P11511 3/20 0.40
ATM Q13315 1/20 0.39
PKM P14618 1/20 0.37
LMNA P02545 2/20 0.36
SCN1A P35498 1/20 0.35
SCN2A Q99250 1/20 0.35
SCN3A Q9NY46 1/20 0.35
GAA P10253 1/20 0.35
XBP1 P17861 1/20 0.35
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7131314 1.00 ALDH1A1 (0.42) ALDH1A1MAPTMEN1KMT2ANPSR1
SCHEMBL7129200 0.93 ALDH1A1 (0.40) ALDH1A1MAPTMEN1KMT2ANPSR1
SCHEMBL18031814 0.89 ALDH1A1 (0.40) ALDH1A1MAPTMEN1KMT2ANPSR1
SCHEMBL11299461 0.83 ALDH1A1 (0.48) ALDH1A1MAPTMEN1KMT2ANPSR1
SCHEMBL7128767 0.82 MEN1 (0.39) ALDH1A1MAPTMEN1KMT2ANPSR1
SCHEMBL7131067 0.82 MEN1 (0.39) ALDH1A1MAPTMEN1KMT2ANPSR1
SCHEMBL7797337 0.82 NPSR1 (0.47) ALDH1A1MAPTMEN1KMT2ANPSR1
SCHEMBL18031825 0.81 CYP17A1 (0.38) ALDH1A1MAPTMEN1KMT2ANPSR1
SCHEMBL10171133 0.80 ALDH1A1 (0.37) ALDH1A1MAPTMEN1KMT2ANPSR1
SCHEMBL15853240 0.80 ALDH1A1 (0.47) ALDH1A1MAPTMEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6670499-B1 Bis-Methacryloyloxy-adamantanedicarboxylate derivatives; raw materials for dental materials and lenses; transparency, luster, hardness, water resistance DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-12-30 US disclosed
EP-1164125-A1 ADAMANTANE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF Daicel Chemical Industries, Ltd. (JP) 2001-12-19 EP disclosed