Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7120797 | 0.93 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL7131314 | 0.93 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL18031814 | 0.85 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL7131070 | 0.84 | MEN1 (0.36) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11299461 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL23636 | 0.79 | THRB (0.48) | ALDH1A1MAPTLMNACYP3A4SMN1; SMN2 | |
| SCHEMBL28149678 | 0.79 | THRB (0.48) | ALDH1A1MAPTLMNACYP3A4SMN1; SMN2 | |
| SCHEMBL7797337 | 0.78 | NPSR1 (0.47) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL18031825 | 0.78 | CYP17A1 (0.38) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL5884750 | 0.77 | THRB (0.47) | ALDH1A1MAPTLMNACYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670499-B1 | Bis-Methacryloyloxy-adamantanedicarboxylate derivatives; raw materials for dental materials and lenses; transparency, luster, hardness, water resistance | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-12-30 | — | — | US | disclosed |
| EP-1164125-A1 | ADAMANTANE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Daicel Chemical Industries, Ltd. (JP) | 2001-12-19 | — | — | EP | disclosed |