Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.51 |
| ▸ | FABP3 | P05413 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475795 | 0.85 | HTT (0.57) | FABP3FABP4FABP5HTTALDH1A1 | |
| SCHEMBL13888684 | 0.83 | MEN1 (0.50) | KCNK3KCNK9HTTALDH1A1MAPT | |
| SCHEMBL7794937 | 0.83 | FABP3 (0.49) | KCNK3KCNK9FABP3FABP4FABP5 | |
| SCHEMBL28370924 | 0.80 | MYC (0.61) | FABP3FABP4FABP5HTTALDH1A1 | |
| SCHEMBL15057628 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MAPTL3MBTL1LMNAKDM4E | |
| SCHEMBL5845535 | 0.77 | FABP4 (0.70) | FABP3FABP4FABP5HTTALDH1A1 | |
| SCHEMBL30036475 | 0.76 | KCNK3 (0.43) | KCNK3KCNK9FABP3FABP4FABP5 | |
| SCHEMBL4600188 | 0.76 | MYC (0.50) | FABP4FABP5ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6681669 | 0.76 | MAOB (0.49) | FABP3FABP4FABP5HTTALDH1A1 | |
| SCHEMBL13937657 | 0.75 | KDM4E (0.62) | FABP3FABP4FABP5HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003047575-A1 | THERAPEUTIC BENZAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-06-12 | — | — | WO | claimed |