Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | FABP3 | P05413 | 1/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475795 | 0.84 | HTT (0.57) | FABP4FABP3FABP5HTTKDM4E | |
| SCHEMBL1966016 | 0.81 | MYC (0.61) | FABP4TAS2R14KDM4ELMNAALDH1A1 | |
| SCHEMBL11230568 | 0.80 | ALDH1A1 (0.54) | FABP4AKR1C3AKR1C2TAS2R14LMNA | |
| SCHEMBL28370924 | 0.79 | MYC (0.61) | FABP4FABP3FABP5HTTKDM4E | |
| SCHEMBL3824168 | 0.78 | FABP4 (0.48) | FABP4TAS2R14PDK2LMNAALDH1A1 | |
| SCHEMBL5782567 | 0.78 | ALDH1A1 (0.51) | MAOBHTTAKR1C3AKR1C2KDM4E | |
| SCHEMBL5788415 | 0.77 | CHEK1 (0.50) | AKR1C3AKR1C2KDM4EALDH1A1HPGD | |
| SCHEMBL4958773 | 0.77 | HSD11B1 (0.46) | PDK2KDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7128802 | 0.76 | KCNK3 (0.51) | FABP4FABP3FABP5HTTKDM4E | |
| SCHEMBL7794937 | 0.76 | FABP3 (0.49) | FABP4FABP3FABP5HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |