SCHEMBL712885

SCHEMBL712885

[c]1ccccc1-c1cc2ccccc2o1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.49
MAOA P21397 3/20 0.49
ALOX5 P09917 1/20 0.46
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
MAPT P10636 1/20 0.45
ADRA2A P08913 2/20 0.44
METAP2 P50579 1/20 0.44
KDM4E B2RXH2 2/20 0.42
HSD17B10 Q99714 2/20 0.42
GRM4 Q14833 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
HPGD P15428 1/20 0.42
ADRA2B P18089 1/20 0.42
ADRA2C P18825 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL103158 0.79 MAOB (0.63) MAOBMAOAALOX5NPC1RAB9A
SCHEMBL30036439 0.79 MAOB (0.63) MAOBMAOAALOX5NPC1RAB9A
SCHEMBL15157317 0.77 APP (0.54) MAOBNPC1RAB9AMAPTADRA2A
SCHEMBL3766008 0.75 ADRA2A (0.50) MAOBMAOAALOX5NPC1RAB9A
SCHEMBL2150499 0.74 MAOB (0.59) MAOBMAOAALOX5NPC1RAB9A
SCHEMBL4810005 0.74 MAOB (0.46) MAOBMAOAALOX5NPC1RAB9A
SCHEMBL1567277 0.73 MAOB (0.62) MAOBMAOAALOX5NPC1RAB9A
SCHEMBL7909606 0.73 NPC1 (0.45) MAOBMAOAALOX5NPC1RAB9A
SCHEMBL4231610 0.73 ADRA2A (0.47) MAOBMAOAALOX5NPC1RAB9A
SCHEMBL2149640 0.73 MAOB (0.57) MAOBMAOAALOX5NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109564972-B Organic light emitting element 株式会社LG化学 2023-02-03 CN claimed
CN-114516804-A Diamine derivative and organic electroluminescent device using same 江苏三月科技股份有限公司 2022-05-20 CN claimed
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN claimed
EP-3579292-B1 ORGANIC LIGHT EMITTING DEVICE LG CHEMICAL LTD (KR) 2020-08-05 EP claimed
EP-3579292-A1 ORGANIC LIGHT EMITTING DEVICE LG Chem, Ltd. (KR) 2019-12-11 EP claimed
CN-109564972-A Organic light emitting element 株式会社LG化学 2019-04-02 CN claimed
CN-106573912-A Triazine compound, method for producing same, and application for same 东曹株式会社 2017-04-19 CN claimed
US-9447065-B2 Pharmaceutical composition RAQUALIA PHARMA INC. (JP) 2016-09-20 US claimed
EP-2979695-A1 THERAPEUTIC AGENT FOR EYE DISORDER AskAt Inc. (JP) 2016-02-03 EP claimed
US-20160008317-A1 THERAPEUTIC AGENT FOR OCULAR DISEASE ASKAT INC. (JP) 2016-01-14 US claimed
EP-1123285-A1 SUBSTITUTED BENZOPYRAN ANALOGS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 2001-08-16 EP claimed
US-6271253-B1 CYCLOOXYGENASE INHIBITORS G.D. SEARLE & CO. 2001-08-07 US claimed
WO-2001049675-A1 DIHYDROBENZOPYRANS, DIHYDROBENZOTHIOPYRANS, AND TETRAHYDROQUINOLINES FOR THE TREATMENT OF COX-2-MEDIATED DISORDERS PHARMACIA CORPORATION (US) 2001-07-12 WO claimed
WO-2001021577-A2 MELANIN CONCENTRATING HORMONE ANTAGONIST TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-03-29 WO claimed
US-6077850-A USEFUL FOR TREATING CYCLOOXYGENASE-2 MEDIATED DISORDERS, SUCH AS INFLAMMATION AND INFLAMMATION-RELATED DISORDERS G.D. SEARLE & CO. (US) 2000-06-20 US claimed
WO-2000023433-A1 SUBSTITUTED BENZOPYRAN ANALOGS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 2000-04-27 WO claimed
US-6034256-A CYCLOOXYGEASE INHIBITOR G.D. SEARLE & CO. (US) 2000-03-07 US claimed
EP-0977748-A1 SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 2000-02-09 EP claimed
WO-1998047890-A1 SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1998-10-29 WO claimed
US-4122256-A OPTICAL BRIGHTENERS HOECHST AKTIENGESELLSCHAFT (DE) 1978-10-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160008317-A1 THERAPEUTIC AGENT FOR OCULAR DISEASE ALDH1A2, PDE6C, PDE6A MAOB 2725/4885MAOA 2417/4885ALOX5 400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.