Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7126974 | 0.86 | SMN1; SMN2 (0.57) | RORCSMN1; SMN2CYP3A4MAPK1PPARG | |
| SCHEMBL5713417 | 0.86 | MITF (0.50) | SMN1; SMN2KMT2AMEN1MAPTLMNA | |
| SCHEMBL31110207 | 0.86 | STAT3 (0.54) | SMN1; SMN2KMT2AMEN1POLBMAPT | |
| SCHEMBL5836520 | 0.85 | SMN1; SMN2 (0.54) | RORCSMN1; SMN2CYP3A4MAPK1PPARG | |
| SCHEMBL343933 | 0.83 | RAB9A (0.58) | SMN1; SMN2CYP3A4KMT2AMEN1GAA | |
| SCHEMBL7130981 | 0.82 | MAPT (0.62) | RORCSMN1; SMN2CYP3A4MAPK1PPARG | |
| SCHEMBL7128392 | 0.79 | SMN1; SMN2 (0.65) | RORCSMN1; SMN2CYP3A4MAPK1PPARG | |
| SCHEMBL7119948 | 0.78 | SMN1; SMN2 (0.83) | RORCSMN1; SMN2CYP3A4MAPK1PPARG | |
| SCHEMBL24074066 | 0.77 | SMN1; SMN2 (0.72) | SMN1; SMN2MAPK1KMT2AMEN1GAA | |
| SCHEMBL7132352 | 0.77 | SMN1; SMN2 (0.60) | RORCSMN1; SMN2CYP3A4MAPK1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1440383-A | PPAR gamma modulators | SANKYO CO (JP) | 2003-09-03 | — | — | CN | disclosed |
| US-20030134859-A1 | PPAR-gamma modulator | SANKYO COMPANY, LIMITED (JP) | 2003-07-17 | — | — | US | disclosed |
| EP-1277729-A1 | PPAR (GAMMA) MODULATORS | Sankyo Company, Limited (JP) | 2003-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030134859-A1 | PPAR-gamma modulator | PPARG, PPARA, PPARD | RORC 67/4885SMN1; SMN2 3743/4885CYP3A4 1516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.