Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | RORC | P51449 | 8/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | PPARA | Q07869 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31665465 | 0.88 | MAPT (0.56) | MAPTPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL7120462 | 0.84 | TASP1 (0.54) | MAPTPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL7162058 | 0.82 | DYRK1A (0.64) | MAPTPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL7129461 | 0.82 | DYRK1A (0.70) | MAPTPOLBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7128930 | 0.82 | RORC (0.59) | MAPTPOLBHTTRORCSMN1; SMN2 | |
| SCHEMBL7128392 | 0.82 | SMN1; SMN2 (0.65) | MAPTPOLBALDH1A1HPGDHTT | |
| SCHEMBL5731624 | 0.81 | MAPT (0.69) | MAPTKDM4EALDH1A1HTTRORC | |
| SCHEMBL27571318 | 0.80 | RORC (0.47) | MAPTPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL7127487 | 0.80 | MMP13 (0.74) | MAPTPOLBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7121680 | 0.80 | KMT2A (0.61) | MAPTPOLBKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1277729-A1 | PPAR (GAMMA) MODULATORS | Sankyo Company, Limited (JP) | 2003-01-22 | — | — | EP | disclosed |