Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 4/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | CCR3 | P51677 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CCR8 | P51685 | 5/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.56 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6496650 | 0.92 | CCR3 (0.74) | OPRL1POLBALDH1A1KDM4ETDP1 | |
| SCHEMBL381873 | 0.88 | OPRL1 (0.75) | OPRL1POLBALDH1A1KDM4ECCR3 | |
| SCHEMBL6529499 | 0.84 | ALDH1A1 (0.65) | OPRL1ALDH1A1KDM4ETDP1HPGD | |
| SCHEMBL7126258 | 0.84 | KDM4E (0.60) | OPRL1ALDH1A1KDM4ETDP1HPGD | |
| SCHEMBL1411499 | 0.83 | OPRL1 (1.00) | OPRL1POLBKDM4ECCR3SIGMAR1 | |
| SCHEMBL6528764 | 0.81 | OPRM1 (0.71) | OPRL1ALDH1A1KDM4ETDP1HPGD | |
| SCHEMBL4816046 | 0.81 | ALDH1A1 (0.80) | OPRL1POLBALDH1A1KDM4ECCR3 | |
| SCHEMBL3893161 | 0.81 | OPRL1 (0.68) | OPRL1POLBKDM4ECCR3DRD2 | |
| SCHEMBL6499571 | 0.80 | ALDH1A1 (0.75) | ALDH1A1KDM4ETDP1HPGDHTT | |
| SCHEMBL6042553 | 0.80 | OPRL1 (0.66) | OPRL1POLBALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003037271-A2 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE THEREFOR | MILLENNIUM PHARMACEUTICALS,INC. (US) | 2003-05-08 | — | — | WO | disclosed |