Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CCR8 | P51685 | 8/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.56 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.55 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129026 | 0.84 | OPRL1 (0.69) | ALDH1A1KDM4ETDP1HPGDHTT | |
| SCHEMBL3252230 | 0.83 | OPRL1 (0.65) | ALDH1A1LMNAGAASIGMAR1OPRM1 | |
| Hydrochloric Acid SCHEMBL6160179 | 0.81 | POLB (0.66) | ALDH1A1LMNAGAASIGMAR1OPRM1 | |
| SCHEMBL27550808 | 0.81 | OPRL1 (0.63) | ALDH1A1LMNAGAASIGMAR1OPRM1 | |
| SCHEMBL6528764 | 0.81 | OPRM1 (0.71) | ALDH1A1KDM4ETDP1HPGDHTT | |
| SCHEMBL7126258 | 0.81 | KDM4E (0.60) | ALDH1A1KDM4ETDP1HPGDHTT | |
| SCHEMBL6499571 | 0.80 | ALDH1A1 (0.75) | ALDH1A1KDM4ETDP1HPGDHTT | |
| SCHEMBL18177893 | 0.79 | ALDH1A1 (0.78) | ALDH1A1KDM4ETDP1HPGDHTT | |
| SCHEMBL6496864 | 0.79 | ALDH1A1 (0.73) | ALDH1A1KDM4ETDP1HPGDHTT | |
| SCHEMBL13743319 | 0.78 | ALDH1A1 (0.70) | ALDH1A1KDM4ETDP1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | MILLENNIUM PHARMACEUTICALS, INC. | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143372-A1 | Compounds, pharmaceutical compositions and methods of use therefor | CCR8, CCL11, CCR5 | ALDH1A1 1071/4885KDM4E 4617/4885TDP1 3425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.