SCHEMBL7129627

SCHEMBL7129627

CCCCCCCC[SiH](c1ccccc1)[Hf](C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.30
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7722031 1.00 SIGMAR1 (0.30) SIGMAR1HTR2A
Hydrochloric Acid SCHEMBL10181385 0.99 KDM4E (0.30) SIGMAR1
SCHEMBL8393088 0.73 SIGMAR1 (0.32) SIGMAR1HTR2A
Hydrochloric Acid SCHEMBL3381748 0.72 SIGMAR1 (0.31) SIGMAR1HTR2A
Hydrochloric Acid SCHEMBL4443280 0.71 HTR6 (0.32) SIGMAR1HTR2A
Hydrochloric Acid SCHEMBL9073221 0.71 HTR6 (0.32) SIGMAR1HTR2A
Hydrochloric Acid SCHEMBL153246 0.71 MEN1 (0.31) SIGMAR1
SCHEMBL21240883 0.71 SIGMAR1 (0.30) SIGMAR1
Hydrochloric Acid SCHEMBL153247 0.71 SIGMAR1 (0.30) SIGMAR1
Hydrochloric Acid SCHEMBL1655211 0.71 SIGMAR1 (0.30) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6667274-B1 Contacting solid alumina, or zirconia, or titania with an electron-withdrawing anion source and metal salt to form an anion-containing solid oxide compound, calcining; no alumoxane necessary; polypropylene PHILLIPS PETROLEUM COMPANY 2003-12-23 US disclosed