Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1655211 | 1.00 | SIGMAR1 (0.30) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL216942 | 0.77 | SIGMAR1 (0.31) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6833671 | 0.75 | SIGMAR1 (0.33) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL217385 | 0.73 | HTR6 (0.32) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7943861 | 0.73 | HTR6 (0.32) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL1655208 | 0.72 | MEN1 (0.31) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL153246 | 0.72 | MEN1 (0.31) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL28559814 | 0.72 | RET (0.35) | SIGMAR1 | |
| SCHEMBL7129627 | 0.71 | SIGMAR1 (0.30) | SIGMAR1 | |
| SCHEMBL7722031 | 0.71 | SIGMAR1 (0.30) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460834-B1 | Improved acidic activator-supports and catalysts for olefin polymerization | CHEVRON PHILLIPS CHEMICAL CO (US) | 2015-08-12 | — | — | EP | claimed |
| EP-1807456-B1 | ORGANOCHROMIUM/METALLOCENE COMBINATION CATALYST FOR PRODUCING BIMODAL RESINS | CHEVRON PHILLIPS CHEMICAL CO (US) | 2012-07-11 | — | — | EP | claimed |
| EP-2460834-A1 | Improved acidic activator-supports and catalysts for olefin polymerization | Chevron Phillips Chemical Company LP (US) | 2012-06-06 | — | — | EP | claimed |
| US-7622414-B2 | Organometal catalyst compositions | CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) | 2009-11-24 | — | — | US | claimed |
| US-20080281063-A9 | Ethylene polymers and copolymers with high optical opacity and methods of making the same | SUKHADIA ASHISH M | 2008-11-13 | — | — | US | claimed |
| US-7417097-B2 | Organometal compound catalyst | PHILLIPS PETROLEUM COMPANY (US) | 2008-08-26 | — | — | US | claimed |
| JP-2008519092-A | — | — | 2008-06-05 | — | — | JP | claimed |
| WO-2006052232-A9 | ORGANOCHROMIUM/ METALLOCENE COMBINATION CATALYST FOR PRODUCING BIMODAL RESINS | CHEVRON PHILLIPS CHEMICAL CO (US) | 2008-02-07 | — | — | WO | claimed |
| US-20080026934-A1 | ACIDIC ACTIVATOR SUPPORTS AND CATALYSTS FOR OLEFIN POLYMERIZATION | CHEVRON PHILLIPS CHEMICAL COMPANY (US) | 2008-01-31 | — | — | US | claimed |
| EP-1807456-A1 | ORGANOCHROMIUM/ METALLOCENE COMBINATION CATALYST FOR PRODUCING BIMODAL RESINS | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2007-07-18 | — | — | EP | claimed |
| US-7163906-B2 | provide polyolefins having very broad molecular weight distribution; comprise the contact product of at least one metallocene compound, at least one organochromium compound, at least one chemically-treated solid oxide, and at least one organoaluminum compound | CHEVRON PHILLIPS CHEMICAL COMPANY, LLP (US) | 2007-01-16 | — | — | US | claimed |
| WO-2006052232-A1 | ORGANOCHROMIUM/ METALLOCENE COMBINATION CATALYST FOR PRODUCING BIMODAL RESINS | CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. (US) | 2006-05-18 | — | — | WO | claimed |
| US-20060094590-A1 | Organochromium/metallocene combination catalysts for producing bimodal resins | CHEVRON PHILLIPS CHEMICAL COMPANY, LP | 2006-05-04 | — | — | US | claimed |
| US-6984603-B2 | Organometal catalyst compositions | PHILLIPS PETROLEUM COMPANY (US) | 2006-01-10 | — | — | US | claimed |
| US-20050288178-A1 | Acidic activator-supports and catalysts for olefin polymerization | CHEVRON PHILLIPS CHEMICAL COMPANY | 2005-12-29 | — | — | US | claimed |
| US-20050203261-A1 | Ethylene polymers and copolymers with high optical opacity and methods of making the same | CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. | 2005-09-15 | — | — | US | claimed |
| US-6858687-B2 | Catalyst compositions that are useful for polymerizing at least one monomer to produce a polymer. This invention also provides catalyst compositions that are useful for polymerizing at least one monomer to produce a polymer, | PHILLIPS PETROLEUM COMPANY (US) | 2005-02-22 | — | — | US | claimed |
| US-6838533-B2 | Organometal catalyst composition | PHILIPS PETROLEUM COMPANY (US) | 2005-01-04 | — | — | US | claimed |
| US-10982023-B2 | Process to produce modified clay, supported metallocene polymerization catalyst | W. R. GRACE & CO.-CONN. (US) | 2021-04-20 | — | — | US | disclosed |
| WO-2001023434-A1 | ORGANOMETAL CATALYST COMPOSITIONS | PHILLIPS PETROLEUM COMPANY (US) | 2001-04-05 | — | — | WO | disclosed |