SCHEMBL7129637

SCHEMBL7129637

ClCC1COCCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11211521 0.97 ALDH1A1 (0.57)
Oxirane SCHEMBL397671 0.86
SCHEMBL7125789 0.80
Propylene Oxide SCHEMBL1756464 0.77 ALDH1A1 (0.65)
SCHEMBL28297160 0.77 CHRM2 (0.44)
SCHEMBL118159 0.76
SCHEMBL3701513 0.76 ALDH1A1 (1.00)
SCHEMBL31018802 0.76
SCHEMBL17976 0.76
SCHEMBL117455 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116199806-B Coordination precipitation polymerization method for olefin polymerization and obtained polyolefin 中国石油化工股份有限公司 2025-05-06 CN disclosed
US-12263159-B2 Fused ring compound having urea structure Sanford Burnham Prebys Medical Discovery Institute (US) 2025-04-01 US disclosed
CN-119627236-A Electrolyte, secondary battery and electricity utilization device 欣旺达动力科技股份有限公司 2025-03-14 CN disclosed
US-12176572-B2 In situ formation of solid-state polymer electrolytes for batteries CORNELL UNIVERSITY (US) 2024-12-24 US disclosed
US-20240285597-A1 FUSED RING COMPOUND HAVING UREA STRUCTURE DAIICHI SANKYO COMPANY LIMITED (JP) 2024-08-29 US disclosed
CN-112654608-B Fused ring compound having urea structure 桑福德伯纳姆普利斯医学发现研究所 2024-05-07 CN disclosed
CN-110770214-B Heterocyclic P2X7 antagonists 布雷耶疗法有限公司 2024-03-29 CN disclosed
US-11918568-B2 Fused ring compound having urea structure Sanford Burnham Prebys Medical Discovery Institute (US) 2024-03-05 US disclosed
CN-116199806-A Coordination precipitation polymerization method for olefin polymerization and obtained polyolefin 中国石油化工股份有限公司 2023-06-02 CN disclosed
US-11623919-B2 Heterocyclic P2X7 antagonists BREYE THERAPEUTICS APS (DK) 2023-04-11 US disclosed
EP-3423445-A1 NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS Galapagos NV (BE) 2019-01-09 EP disclosed
WO-2018202694-A1 HETEROCYCLIC P2X7 ANTAGONISTS AXXAM S.P.A. (IT) 2018-11-08 WO disclosed
EP-3398941-A1 HETEROCYCLIC P2X7 ANTAGONISTS AXXAM S.p.A. (IT) 2018-11-07 EP disclosed
WO-2017132459-A1 DNA ALKYLATION AND CROSS-LINKING AGENTS AS COMPOUNDS AND PAYLOADS FOR TARGETED THERAPIES YALE UNIVERSITY (US) 2017-08-03 WO disclosed
CN-103764708-B Photopolymerizable composition, photopolymerizable coating agent, laminate, and polarizing plate 东洋油墨SC控股株式会社 2016-12-14 CN disclosed
CN-101492463-B Imidazopyridine derivative containing dioxane-pyridine SHANDONG XUANZHU PHARM TECH CO 2011-01-12 CN disclosed
CN-101492463-A Imidazopyridine derivative containing dioxane-pyridine SHANDONG XUANZHU PHARM TECH CO (CN) 2009-07-29 CN disclosed
US-6667412-B1 Carboxylic acid, ester or alcohol derivatives; n,n-substi-tuted cyclic amine or phenylacetonitrile intermediates; low cost; stability, workability, final product purity EISAI CO., LTD. (JP) 2003-12-23 US disclosed
EP-1167348-A1 NITRILE DERIVATIVES Eisai Co., Ltd. (JP) 2002-01-02 EP disclosed
US-5116402-A HERBICIDAL COMPOSITION CONTAINING DIOXOLANE, DIOXANE, OR DIOXEPANE DERIVATIVES AS ANTIDOTE MAGYAR TUDOMANVOS AKADEMIA KOZPONTI KEMIAI KUTATO INTEZETE NITROKEMIA INARTELENEK FUZFOGYARTELEP (HU) 1992-05-26 US disclosed