Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 4/20 | 0.33 |
| ▸ | EDNRB | P24530 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6293067 | 0.87 | PIK3CD (0.45) | PIK3CDMALT1EDNRAEDNRBALDH1A1 | |
| SCHEMBL6289882 | 0.87 | HPGD (0.40) | PIK3CDMALT1EDNRAEDNRBALDH1A1 | |
| SCHEMBL6293273 | 0.85 | FBP1 (0.36) | PIK3CDMALT1ALDH1A1MAPTKDM4E | |
| SCHEMBL6292720 | 0.84 | PIK3CD (0.39) | PIK3CDMALT1EDNRAEDNRBALDH1A1 | |
| SCHEMBL6292822 | 0.84 | EDNRB (0.43) | EDNRB | |
| SCHEMBL6293113 | 0.83 | LMNA (0.34) | PIK3CDMALT1EDNRAEDNRBGAA | |
| SCHEMBL6292724 | 0.81 | EDNRB (0.46) | EDNRAEDNRB | |
| SCHEMBL6292702 | 0.81 | FYN (0.34) | PIK3CDMALT1EDNRBALDH1A1MAPT | |
| SCHEMBL6289667 | 0.77 | PIK3CD (0.37) | PIK3CDMALT1EDNRBALDH1A1MAPT | |
| SCHEMBL6293084 | 0.77 | KMT2A (0.42) | MALT1ALDH1A1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232848-A1 | Pyrazole compositions | PFIZER INC. | 2003-12-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232848-A1 | Pyrazole compositions | EDNRB, EDNRA, AGTR1 | PIK3CD 1459/4885MCL1 2199/4885MALT1 2189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.