SCHEMBL7129765

SCHEMBL7129765

O=c1oc2cc(O)c(O)cc2cc1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.56
LMNA P02545 2/20 0.50
AKR1B1 P15121 2/20 0.50
HPGD P15428 2/20 0.50
XDH P47989 2/20 0.50
MCL1 Q07820 2/20 0.50
CA12 O43570 2/20 0.50
CA9 Q16790 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP1A2 P05177 1/20 0.50
BCHE P06276 1/20 0.50
GLA P06280 1/20 0.50
CYP3A4 P08684 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
ALOX15 P16050 1/20 0.50
ACHE P22303 1/20 0.50
PTGS1 P23219 1/20 0.50
CASP1 P29466 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15843061 0.83 MAOB (0.64) MAOBLMNACA12CA9KDM4E
SCHEMBL2791740 0.83 AKR1B1 (0.61) LMNAAKR1B1HPGDXDHMCL1
SCHEMBL17942935 0.78 HSD17B3 (0.56) MAOBLMNAAKR1B1HPGDXDH
SCHEMBL10794088 0.77 MAOB (0.68) MAOBLMNAHPGDMCL1CA12
SCHEMBL10791318 0.77 MIF (0.65) MAOBAKR1B1HPGDMCL1CA12
SCHEMBL17867030 0.76 SMN1; SMN2 (0.53) LMNAAKR1B1HPGDXDHMCL1
SCHEMBL3079488 0.76 HSD17B3 (0.62) MAOBLMNAAKR1B1HPGDXDH
SCHEMBL8315657 0.76 MAOB (0.61) MAOBLMNAAKR1B1HPGDXDH
SCHEMBL14405907 0.75 MAOB (0.60) MAOBLMNACA12CA9KDM4E
SCHEMBL530998 0.75 GPR35 (0.68) MAOBHPGDCA12CA9KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2003246785-A METHOD FOR MANUFACTURING 6,7-DIHYDROXYCOUMARIN UBE IND LTD 2003-09-02 JP disclosed
JP-2003238553-A 3-CHLORO-6,7-DIHYDROXYCOUMARIN AND METHOD FOR PRODUCING THE SAME UBE IND LTD 2003-08-27 JP disclosed