SCHEMBL7129959

SCHEMBL7129959

O=C=NCC1CC2C=CC1C2

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.42
ALDH1A1 P00352 3/20 0.42
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 3/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HTT P42858 1/20 0.32
LMNA P02545 1/20 0.32
EPHX2 P34913 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL339490 0.74 KDM4E (0.42) KDM4EALDH1A1TSHRTDP1MEN1
SCHEMBL16705165 0.72 EPHX1 (0.41) KDM4EALDH1A1
SCHEMBL16704810 0.72 EPHX1 (0.41) KDM4EALDH1A1
SCHEMBL22899096 0.71
SCHEMBL7873134 0.71
SCHEMBL5494092 0.71 KDM4E (0.40) KDM4EALDH1A1TSHRTDP1MEN1
SCHEMBL154141 0.70
SCHEMBL4445948 0.69 KDM4E (0.48) KDM4EALDH1A1TSHRTDP1MEN1
SCHEMBL1012047 0.69 KDM4E (0.48) KDM4EALDH1A1TSHRTDP1MEN1
SCHEMBL14000210 0.67 POLB (0.30) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3992694-A1 METHOD FOR MANUFACTURING SPECTACLE LENS, SPECTACLE LENS, AND SPECTACLES Hoya Lens Thailand Ltd. (TH) 2022-05-04 EP claimed
EP-3992224-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS, OPTICAL MATERIAL, AND METHOD FOR PRODUCING OPTICAL MATERIAL Hoya Lens Thailand Ltd. (TH) 2022-05-04 EP claimed
US-20220120936-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND METHOD FOR PRODUCING OPTICAL MATERIAL HOYA LENS THAILAND LTD. (TH) 2022-04-21 US claimed
US-20220112327-A1 METHOD FOR PRODUCING SPECTACLE LENS, SPECTACLE LENS, AND SPECTACLES HOYA LENS THAILAND LTD. (TH) 2022-04-14 US claimed
CN-114008097-A Method for manufacturing spectacle lens, and spectacles 豪雅镜片泰国有限公司 2022-02-01 CN claimed
US-12630738-B2 In-mold coating crosslinkers, compositions, systems, processes and articles RED SPOT PAINT & VARNISH CO., INC. (US) 2026-05-19 US disclosed
US-20230086386-A1 IN-MOLD COATING CROSSLINKERS, COMPOSITIONS, SYSTEMS, PROCESSES AND ARTICLES RED SPOT PAINT & VARNISH CO., INC. (US) 2023-03-23 US disclosed
WO-2022241234-A1 IN-MOLD COATING CROSSLINKERS, COMPOSITIONS, SYSTEMS, PROCESSES AND ARTICLES RED SPOT PAINT & VARNISH CO., INC. (US) 2022-11-17 WO disclosed
EP-3992224-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS, OPTICAL MATERIAL, AND METHOD FOR PRODUCING OPTICAL MATERIAL Hoya Lens Thailand Ltd. (TH) 2022-05-04 EP disclosed
EP-3992694-A1 METHOD FOR MANUFACTURING SPECTACLE LENS, SPECTACLE LENS, AND SPECTACLES Hoya Lens Thailand Ltd. (TH) 2022-05-04 EP disclosed
EP-3992694-A1 METHOD FOR MANUFACTURING SPECTACLE LENS, SPECTACLE LENS, AND SPECTACLES Hoya Lens Thailand Ltd. (TH) 2022-05-04 EP disclosed
US-20220120936-A1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND METHOD FOR PRODUCING OPTICAL MATERIAL HOYA LENS THAILAND LTD. (TH) 2022-04-21 US disclosed
WO-2020262660-A1 METHOD FOR MANUFACTURING SPECTACLE LENS, SPECTACLE LENS, AND SPECTACLES ホヤ レンズ タイランド リミテッド 2020-12-30 WO disclosed
CN-100487002-C Nitrogen-oxygen nickel complex catalytic system and preparation and application thereof PETROCHINA CO LTD (CN) 2009-05-13 CN disclosed
CN-101092459-A supported polymerization catalytic system and preparation method and application thereof PETROCHINA CO LTD (CN) 2007-12-26 CN disclosed
CN-1597116-A Nitrogen-oxygen nickel complex catalytic system and preparation and application thereof CHINA NAT PETROLEUM CORP (CN) 2005-03-23 CN disclosed
CN-1128158-C Catalysis system f nitrogen-phosphinonickel matches and its preparing process and application CHINESE ACAD INST CHEMISTRY (CN) 2003-11-19 CN disclosed
JP-2003286241-A METHOD FOR PRODUCING BICYCLO[2.2.1]HEPT-2-ENE-5-METHYL ISOCYANATE MITSUI TAKEDA CHEMICALS INC 2003-10-10 JP disclosed
CN-1390644-A Catalysis system f nitrogen-phosphinonickel matches and its preparing process and application CHINESE ACAD INST CHEMISTRY (CN) 2003-01-15 CN disclosed
US-3966797-A Dinorbornenes UNION CARBIDE CORPORATION (US) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630738-B2 In-mold coating crosslinkers, compositions, systems, processes and articles UROD, DUOX1, PDCD2L KDM4E 1615/4885ALDH1A1 666/4885TSHR 4843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.