⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16739657 | 1.00 | ALDH1A1 (0.56) | — | |
| SCHEMBL8349207 | 0.97 | ALDH1A1 (0.54) | — | |
| Bromopyruvate SCHEMBL29058425 | 0.91 | ALDH1A1 (0.48) | — | |
| SCHEMBL8630186 | 0.85 | ALDH1A1 (0.52) | — | |
| SCHEMBL28614733 | 0.81 | ALDH1A1 (0.48) | — | |
| SCHEMBL10644453 | 0.80 | FAAH (0.47) | — | |
| SCHEMBL274916 | 0.80 | ALDH1A1 (0.41) | — | |
| SCHEMBL7103340 | 0.80 | NPSR1 (0.50) | — | |
| SCHEMBL7103341 | 0.80 | NPSR1 (0.50) | — | |
| SCHEMBL8920168 | 0.78 | ALDH1A1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5559 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122060333-A | High-temperature-resistant silicon rubber and preparation method and application thereof | 东莞宏强新材料有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-120081843-A | Fluorescent probe for quantitatively detecting NO in exhaled breath, and preparation method and application thereof | 阜阳师范大学 | 2025-06-03 | — | — | CN | claimed |
| CN-119320363-A | Oxazole disubstituted compound, preparation method and application | 中国科学院大连化学物理研究所 | 2025-01-17 | — | — | CN | claimed |
| CN-119259264-A | Method for recovering and extracting noble metal from mineral dressing tailings | 江西一元再生资源有限公司 | 2025-01-07 | — | — | CN | claimed |
| US-12098132-B2 | Process for preparation of aldehyde scavenger and intermediates | ALDEYRA THERAPEUTICS, INC. (US) | 2024-09-24 | — | — | US | claimed |
| CN-117756848-A | TH-302 derivative and preparation method thereof | 常州大学 | 2024-03-26 | — | — | CN | claimed |
| CN-113501819-B | Pyridoimidazole substituted quinazolinone derivative, and synthetic method and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2024-02-02 | — | — | CN | claimed |
| CN-117384164-A | Preparation method of quinoxaline derivative | 上海睿智化学研究有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-117209488-A | Alkaloid barakacin derivative, synthesis thereof and application thereof in prevention and treatment of plant virus and germ diseases | 天津师范大学 | 2023-12-12 | — | — | CN | claimed |
| CN-116969902-A | Compound containing phenylthiazole acylhydrazone structure, and preparation and application thereof | 长江大学 | 2023-10-31 | — | — | CN | claimed |
| WO-2009135581-A2 | NOVEL NIP THIAZOLE DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE-1 | MERCK PATENT GMBH (DE) | 2009-11-12 | — | — | WO | claimed |
| US-20090203715-A1 | NOVEL 2-HETARYLTHIAZOLE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND USE AS PHARMACEUTICALS | BAYER SCHERING PHARMA AG (DE) | 2009-08-13 | — | — | US | claimed |
| WO-2009018368-A1 | COMBINATION TREATMENT OF NMDA (N-METHYL-D-ASPARTATE)-ENHANCER, GLYCINE TRANSPORTER INHIBITOR, D-AMINO ACID OXIDASE INHIBITOR (DAAOI) FOR NEUROPSYCHIATRIC DISORDERS | LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER (US) | 2009-02-05 | — | — | WO | claimed |
| WO-2007052882-A1 | PYRIDINE THIAZOLE CARBOXAMIDE DERIVATIVES, THE PREPARATION METHOD THEREOF, AND THE COMPOSITION FOR SKIN WHITENING CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2007-05-10 | — | — | WO | claimed |
| EP-1773331-A1 | IMIDAZOLE AND THIAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2007-04-18 | — | — | EP | claimed |
| WO-2006008556-A1 | IMIDAZOLE AND THIAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2006-01-26 | — | — | WO | claimed |
| WO-2000026177-A1 | SYNTHESIS OF ETHYL BROMOPYRUVATE | GREAT LAKES CHEMICAL CORPORATION (US) | 2000-05-11 | — | — | WO | claimed |
| EP-0171171-B1 | A PROCESS FOR PREPARING 2-BETA-D-RIBOFURANOSYLSELENAZOLE-4-CARBOXAMIDE | WARNER-LAMBERT COMPANY (US) | 1990-04-25 | — | — | EP | claimed |
| US-4619996-A | Process for preparing 2-β-D-ribofuranosylselenazole-4-carboxamide | WARNER-LAMBERT COMPANY (US) | 1986-10-28 | — | — | US | claimed |
| EP-0171171-A1 | A process for preparing 2-beta-D-ribofuranosylselenazole-4-carboxamide | WARNER-LAMBERT COMPANY (US) | 1986-02-12 | — | — | EP | claimed |