Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11445339 | 0.86 | ALDH1A1 (0.52) | ALDH1A1HCAR2FAAHSMN1; SMN2TSHR | |
| SCHEMBL5174796 | 0.85 | TSHR (0.55) | ALDH1A1HCAR2FAAHTSHRLMNA | |
| SCHEMBL11433560 | 0.83 | TSHR (0.58) | ALDH1A1HCAR2FAAHTSHRLMNA | |
| SCHEMBL19813741 | 0.83 | TSHR (0.58) | ALDH1A1HCAR2FAAHTSHRLMNA | |
| SCHEMBL19813747 | 0.83 | TSHR (0.58) | ALDH1A1HCAR2FAAHTSHRLMNA | |
| SCHEMBL7108037 | 0.81 | HCAR2 (0.37) | ALDH1A1TRPA1HCAR2FAAHGAA | |
| SCHEMBL7108033 | 0.81 | HCAR2 (0.37) | ALDH1A1TRPA1HCAR2FAAHGAA | |
| SCHEMBL16044867 | 0.80 | HCAR2 (0.41) | ALDH1A1HCAR2FAAHGAASMN1; SMN2 | |
| SCHEMBL3020479 | 0.80 | HCAR2 (0.41) | ALDH1A1HCAR2FAAHGAASMN1; SMN2 | |
| SCHEMBL16045838 | 0.80 | GAA (0.43) | ALDH1A1HCAR2GAASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260022384-A1 | ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF | OSPEDALE SAN RAFFAELE S.R.L. (IT) | 2026-01-22 | — | — | US | claimed |
| WO-2025042868-A1 | COMBINATIONS OF HETEROAROTINOIDS AND GLYCOLYTIC INHIBITORS FOR USE AS CANCER TREATMENTS | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2025-02-27 | — | — | WO | claimed |
| US-20250017950-A1 | COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS | UCL BUSINESS LTD (GB) | 2025-01-16 | — | — | US | claimed |
| EP-4433077-A1 | COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS | UCL Business Ltd (GB) | 2024-09-25 | — | — | EP | claimed |
| CN-221528993-U | Optical system | 浙江舜宇光学有限公司 | 2024-08-13 | — | — | CN | claimed |
| CN-117310997-A | Optical system | 浙江舜宇光学有限公司 | 2023-12-29 | — | — | CN | claimed |
| US-20230181621-A1 | ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF | OSPEDALE SAN RAFFAELE S.R.L. (IT) | 2023-06-15 | — | — | US | claimed |
| WO-2023089313-A1 | COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS | UCL BUSINESS LTD (GB) | 2023-05-25 | — | — | WO | claimed |
| CN-115933203-A | Optical system and VR equipment including the same | 浙江舜宇光学有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-115149932-A | Mixed modulation method for restraining EMI (electro-magnetic interference) applied to motor driving chip | 嘉兴禾润电子科技有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-114212063-A | Method and device for determining electronic parking clamping force | 中国第一汽车股份有限公司 | 2022-03-22 | — | — | CN | claimed |
| WO-2022055285-A1 | PHARMACEUTICAL COMPOSITION FOR KILLING CANCER PROGENITOR CELLS | 연세대학교 산학협력단 | 2022-03-17 | — | — | WO | claimed |
| CN-115712191-B | Large aperture lens | 舜宇光学(中山)有限公司 | 2026-05-19 | — | — | CN | disclosed |
| US-20260022384-A1 | ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF | OSPEDALE SAN RAFFAELE S.R.L. (IT) | 2026-01-22 | — | — | US | disclosed |
| CN-120150892-A | Phase passive compensation method and device for wavelength division multiplexing long-distance optical transmission link | 中国电子科技集团公司第三十八研究所 | 2025-06-13 | — | — | CN | disclosed |
| CN-120060152-A | Cell model for high-throughput screening of 2-DG anti-renal cancer drugs and construction method and application thereof | 宿州学院 | 2025-05-30 | — | — | CN | disclosed |
| US-20050054634-A1 | Modulating active of receptors; therapy prevention of disease such aas symthrome X, antidiabetic agents, insulin resistance, hypoglycemic agents | AKARNA THERAPEUTICS, LTD. (GB) | 2005-03-10 | — | — | US | disclosed |
| US-20040023947-A1 | Azepinoindole and pyridoindole derivatives as pharmaceutical agents | X-CEPTOR THERAPEUTICS INC. | 2004-02-05 | — | — | US | disclosed |
| WO-2003099821-A1 | AZEPINOINDOLE AND PYRIDOINDOLE DERIVATIVES AS PHARMACEUTICAL AGENTS | X-CEPTOR THERAPEUTICS, INC. (US) | 2003-12-04 | — | — | WO | disclosed |
| US-4560690-A | ANTISECRETORY AGENTS, HISTAMINE H2-ANTAGONISTS | PFIZER INC. (US) | 1985-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040023947-A1 | Azepinoindole and pyridoindole derivatives as pharmaceutical agents | HTR5A, MTNR1A, PTGDR | ALDH1A1 1722/4885TRPA1 754/4885HCAR2 64/4885 |
| US-20230181621-A1 | ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF | ASNS, GLS, GLS2 | ALDH1A1 2207/4885TRPA1 4764/4885HCAR2 1976/4885 |
| US-20250017950-A1 | COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS | POLRMT, TK2, GOT2 | ALDH1A1 1791/4885TRPA1 4851/4885HCAR2 2884/4885 |
| US-20050054634-A1 | Modulating active of receptors; therapy prevention of disease such aas symthrome X, antidiabetic agents, insulin resistance, hypoglycemic agents | GPR119, IRS1, INSR | ALDH1A1 3963/4885TRPA1 459/4885HCAR2 38/4885 |
| US-20260022384-A1 | ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF | ASNS, AARS1, NARS1 | ALDH1A1 3160/4885TRPA1 3648/4885HCAR2 4766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.